Article
A1166C polymorphism of the angiotensin II type 1 receptor gene contributes to hypertension susceptibility: evidence from a meta-analysis.
Acta cardiologica - 1 Apr 2017
Yang Yujuan, Tian Tao, Lu Jun, He Hairong, Xing Kun, Tian Gang
Abstract excerpt
Background The angiotensin II type 1 receptor (AT1R) gene is a prime candidate for polymorphisms that could contribute to hypertension. A polymorphism in the 3' untranslated region, leading to the transversion of adenine to cytosine at position 1166, has been the most-studied variant. However, the results have been inconsistent, and we therefore performed a meta-analysis to evaluate the association of this...
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