Article
Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2010
Shu Xiao, Nelbach Lisa, Weinstein Michael M, Burgess Braydon L, Beckstead Jennifer A, Young Stephen G, Ryan Robert O, Forte Trudy M
Abstract excerpt
OBJECTIVE: Apolipoprotein A-V (apoA-V), a minor protein associated with lipoproteins, has a major effect on triacylglycerol (TG) metabolism. We investigated whether apoA-V complexed with phospholipid in the form of a reconstituted high-density lipoprotein (rHDL) has potential utility as a therape...
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