Article
Apoprotein A-V: an important regulator of triglyceride metabolism.
Journal of inherited metabolic disease - 1 Apr 2008
Kluger M, Heeren J, Merkel M
Abstract excerpt
Apolipoprotein A-V (apoA-V) was discovered in 2001 both by comparative sequencing and as a liver regeneration protein. The gene is a located at the APOA1/C3/A4/A5 gene cluster on chromosome 11q23, a locus well known for playing a major role in regulating plasma cholesterol and triglyceride (TG) levels. ApoA-V is produced in the liver and has very low plasma concentrations (0.1-0.4 mug/ml). Mice lacking apoA-V...
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