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Article

In vitro activity of cethromycin against Burkholderia pseudomallei and investigation of mechanism of resistance.

The Journal of antimicrobial chemotherapy - 1 Jan 2011

Mima Takehiko, Schweizer Herbert P, Xu Ze-Qi

Abstract excerpt

OBJECTIVES: most Burkholderia pseudomallei strains are intrinsically resistant to macrolides, mainly due to AmrAB-OprA- and/or BpeAB-OprB-mediated efflux. We assessed the in vitro anti-B. pseudomallei efficacy of cethromycin, a novel ketolide with broad-spectrum activity against Gram-negative and Gram-positive pathogens. METHODS: the 2-fold broth microdilution technique was used to assess the in vitro cethromycin...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20965890
DOI: 10.1093/jac/dkq391
PMCID: PMC3001848

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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