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Plant Metabolites as Potential Agents That Potentiate or Block Resistance Mechanisms Involving β-Lactamases and Efflux Pumps

10 Jun 2025

Abstract excerpt

The dramatic increase in antimicrobial resistance (AMR) in recent decades has created an urgent need to develop new antimicrobial agents and compounds that can modify and/or block bacterial resistance mechanisms. An understanding of these resistance mechanisms and how to overcome them would substantially assist in the development of new antibiotic chemotherapies. Bacteria may develop AMR through multiple...

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Berberine and alkaloids research
Chemical synthesis and alkaloids
Essential Oils and Antimicrobial Activity

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PMID: 40565013
DOI: 10.3390/ijms26125550

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