Article
Past, present and future of myoblast transplantation in the treatment of Duchenne muscular dystrophy.
Pediatric transplantation - 1 Nov 2010
Palmieri Beniamino, Tremblay Jacques P, Daniele Lodi
Abstract excerpt
DMD is a genetic X-linked recessive disease that affects approximately one in 3500 male births. Boys with DMD have progressive and predictable muscle destruction because of the absence of Dys, a protein present under the muscle fiber membrane. Dys deficiency induces contraction-related membrane damages, activation of inflammatory-necrosis-fibrosis up to the cardiac-diaphragmatic failure and death. This review...
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