Article
Co-Transplantation of Bone Marrow-MSCs and Myogenic Stem/Progenitor Cells from Adult Donors Improves Muscle Function of Patients with Duchenne Muscular Dystrophy.
Cells - 30 Apr 2020
Klimczak Aleksandra, Zimna Agnieszka, Malcher Agnieszka, Kozlowska Urszula, Futoma Katarzyna, Czarnota Jaroslaw, Kemnitz Pawel, Bryl Anna, Kurpisz Maciej
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a genetic disorder associated with a progressive deficiency of dystrophin that leads to skeletal muscle degeneration. In this study, we tested the hypothesis that a co-transplantation of two stem/progenitor cell populations, namely bone marrow-derived mesenchymal stem cells (BM-MSCs) and skeletal muscle-derived stem/progenitor cells (SM-SPCs), directly into the dystrophic...
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