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Systemic cell therapy for muscular dystrophies

21 Dec 2020

Abstract excerpt

The intrinsic regenerative capacity of skeletal muscle makes it an excellent target for cell therapy. However, the potential of muscle tissue to renew is typically exhausted and insufficient in muscular dystrophies (MDs), a large group of heterogeneous genetic disorders showing progressive loss of skeletal muscle fibers. Cell therapy for MDs has to rely on suppletion with donor cells with high myogenic...

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PMID: 33349909
DOI: 10.1007/s12015-020-10100-y

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