Article

Dental Pulp Stromal Cells Can Improve Muscle Dysfunction 1 in Animal Models of Duchenne Muscular Dystrophy

2020-10-21

Abstract excerpt

<title>Abstract</title> <p>Background: Duchenne muscular dystrophy (DMD) is an inherited progressive disorder that causes skeletal and cardiac muscle deterioration with chronic inflammation. Dental pulp stromal cells (DPSCs) are attractive candidates for cell-based strategies for DMD because of their immunosuppressive properties. Therefore, we hypothesized that systemic treatment with DPSCs might show therapeutic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 865329ed-099d-5a3a-a82f-d9ba8e767a9c
DOI: 10.21203/rs.3.rs-94158/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dental Pulp Stromal Cells Can Improve Muscle Dysfunction 1 in Animal Models of Duchenne Muscular DystrophyDOI 10.21203/rs.3.rs-94158/v1Read

Enhanced cell survival and therapeutic benefits of IL-10-expressing multipotent mesenchymal stromal cells for muscular dystrophySemantic proximity Read

Improving the therapeutic efficacy of gene therapy for duchenne muscular dystrophy (DMD) by evaluating and managing inflammationSemantic proximity Read

Past, present and future of myoblast transplantation in the treatment of Duchenne muscular dystrophy.Semantic proximity Read

Duchenne muscular dystrophy: pathogenesis and promising therapies.Semantic proximity Read

Current understanding of dystrophin-related muscular dystrophy and therapeutic challenges ahead.Semantic proximity Read

Therapeutic aspects of cell signaling and communication in Duchenne muscular dystrophySemantic proximity Read

Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future.Semantic proximity Read

Human induced pluripotent stem cell models for the study and treatment of Duchenne and Becker muscular dystrophiesSemantic proximity Read

Human dental pulp pluripotent-like stem cells promote wound healing and muscle regenerationSemantic proximity Read

Transplantation of dental pulp stem cells suppressed inflammation in sciatic nerves by promoting macrophage polarization towards anti-inflammation phenotypes and ameliorated diabetic polyneuropathy.Semantic proximity Read

Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model.Semantic proximity Read

Co-Transplantation of Bone Marrow-MSCs and Myogenic Stem/Progenitor Cells from Adult Donors Improves Muscle Function of Patients with Duchenne Muscular Dystrophy.Semantic proximity Read