Article
Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2011
Shook Devon, Brady Colin, Lee Philip S, Kenealy Laura, Murphy Eric R, Gaillard William D, VanMeter John W, Cook Edwin H, Stein Mark, Vaidya Chandan J
Abstract excerpt
Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head...
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