Article
A Population-Based Imaging Genetics Study of Inattention/Hyperactivity: Basal Ganglia and Genetic Pathways.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Sept 2015
Mous Sabine E, Hammerschlag Anke R, Polderman Tinca J C, Verhulst Frank C, Tiemeier Henning, van der Lugt Aad, Jaddoe Vincent W, Hofman Albert, White Tonya, Posthuma Danielle
Abstract excerpt
OBJECTIVE: Although attention-deficit/hyperactivity disorder (ADHD) is 1 of the most common neurodevelopmental disorders, little is known about the neurobiology. Clinical studies suggest basal ganglia morphology plays a role. Furthermore, hyperactivity/impulsivity symptoms have recently been linked to genetic pathways involved in dopamine/norepinephrine and serotonin neurotransmission and neuritic outgrowth. We...
Topics
- Attention Deficit Disorder with Hyperactivity
- Behavior Rating Scale
- Child
- Cohort Studies
- Female
- Genome-Wide Association Study
- Humans
- Hyperkinesis
- Impulsive Behavior