Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder.

doi:10.1016/j.jaac.2017.02.009

Article

Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 May 2017

Xu Bing, Jia Tianye, Macare Christine, Banaschewski Tobias, Bokde Arun L W, Bromberg Uli, Büchel Christian, Cattrell Anna, Conrod Patricia J, Flor Herta, Frouin Vincent, Gallinat Jürgen, Garavan Hugh, Gowland Penny, Heinz Andreas, Ittermann Bernd, Martinot Jean-Luc, Paillère Martinot Marie-Laure, Nees Frauke, Orfanos Dimitri Papadopoulos, Paus Tomáš, Poustka Luise, Smolka Michael N, Walter Henrik, Whelan Robert, Schumann Gunter, Desrivières Sylvane

Abstract excerpt

OBJECTIVE: In a recent genomewide association study of subcortical brain volumes, a common genetic variation at rs945270 was identified as having the strongest effect on putamen volume, a brain measurement linked to familial risk for attention-deficit/hyperactivity disorder (ADHD). To determine whether rs945270 might be a genetic determinant of ADHD, its effects on ADHD-related symptoms and neural mechanisms of...

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Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder.

Abstract excerpt

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