Article
Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.
Molecular psychiatry - 1 Sept 2011
Stein J L, Hibar D P, Madsen S K, Khamis M, McMahon K L, de Zubicaray G I, Hansell N K, Montgomery G W, Martin N G, Wright M J, Saykin A J, Jack C R, Weiner M W, Toga A W, Thompson P M
Abstract excerpt
The caudate is a subcortical brain structure implicated in many common neurological and psychiatric disorders. To identify specific genes associated with variations in caudate volume, structural magnetic resonance imaging and genome-wide genotypes were acquired from two large cohorts, the Alzheimer's Disease NeuroImaging Initiative (ADNI; N=734) and the Brisbane Adolescent/Young Adult Longitudinal Twin Study...
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