Article
An investigation of the robustness of the consensus method of interpreting low-template DNA profiles.
Forensic science international. Genetics - 1 Nov 2011
Cowen Simon, Debenham Paul, Dixon Alan, Kutranov Stefan, Thomson Jim, Way Kerry
Abstract excerpt
Forensic STR profiles generated from low-template DNA samples are more noticeably subject to effects such as allele dropout, contamination with spurious alleles ('drop-in') and proportionally larger stutter. The profiles obtained are frequently partial, and are challenging to interpret. Specifically, interpretation guidelines which are used when the template DNA is in the optimal range for the STR test kit in use...
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