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Interpreting low template DNA profiles.

Forensic science international. Genetics - 1 Dec 2009

Balding David J, Buckleton John

Abstract excerpt

We discuss the interpretation of DNA profiles obtained from low template DNA samples. The most important challenge to interpretation in this setting arises when either or both of "drop-out" and "drop-in" create discordances between the crime scene DNA profile and the DNA profile expected under the prosecution allegation. Stutter and unbalanced peak heights are also problematic, in addition to the effects of...

Topics

DNA
DNA Fingerprinting
Gene Frequency
Genotype
Humans
Likelihood Functions
Loss of Heterozygosity
Polymerase Chain Reaction
Probability

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19948328
DOI: 10.1016/j.fsigen.2009.03.003

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