Case report: Statin-induced rhabdomyolysis in a patient with SCLO1B1 gene abnormalities

Abstract excerpt

<title>Abstract</title> <p>Statin use can cause rhabdomyolysis, especially in patients with abnormalities in the SCLO1B1 gene, which transports statins into hepatocytes. We report a case study of a 53-year-old male patient with a mutation in the SCLO1B1 gene who was diagnosed with rhabdomyolysis complicated by acute kidney injury requiring renal replacement therapy. This case study highlights the importance of ea...

Topics

Open a Topic to create a Post that cites this publication.

• Atorvastatin
• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• Hypercholesterolemia
• Liver-Specific Organic Anion Transporter 1
• Muscular Diseases
• Polymorphism, Single Nucleotide
• Proprotein Convertase 9
• Rhabdomyolysis

Identifiers and source

Literature Corpus work

54ea2d31-9033-5000-8bf7-8f4a5f881fc1

DOI

10.21203/rs.3.rs-4505333/v1