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Article

Strand transfer and elongation of HIV-1 reverse transcription is facilitated by cell factors in vitro.

PloS one - 6 Oct 2010

Warrilow David, Warren Kylie, Harrich David

Abstract excerpt

Recent work suggests a role for multiple host factors in facilitating HIV-1 reverse transcription. Previously, we identified a cellular activity which increases the efficiency of HIV-1 reverse transcription in vitro. Here, we describe aspects of the activity which shed light on its function. The cellular factor did not affect synthesis of strong-stop DNA but did improve downstream DNA synthesis. The stimulatory...

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Identifiers

PMID: 20949087
DOI: 10.1371/journal.pone.0013229
PMCID: PMC2950853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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