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Article

Reverse Transcription Takes Place within Extracellular HIV-1 Virions: Potential Biological Significance

1 Dec 1993

Abstract excerpt

Extracellular HIV-1 virions purified from cell culture supernatants have been found to contain viral DNA that is the result of partial reverse transcription within the virus particles. Our data supported these observations and further indicated that the ratio of genomic RNA to viral DNA was approximately 10(3):1 for the "strong stop" (R-U5) region and 10(5):1 for the gag region. We have shown that, in the absence...

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Identifiers

PMID: 8142146
DOI: 10.1089/aid.1993.9.1287

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Research trail→

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Reverse Transcription Takes Place within Extracellular HIV-1 Virions: Potential Biological SignificancePMID 8142146Read ↗

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Cell Factors Stimulate Human Immunodeficiency Virus Type 1 Reverse Transcription In VitroSemantic proximity Read ↗

Role of Vif in human immunodeficiency virus type 1 reverse transcriptionSemantic proximity Read ↗

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