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Characterization of Intracellular Reverse Transcription Complexes of Human Immunodeficiency Virus Type 1

15 Apr 2001

Abstract excerpt

To examine the early events of the life cycle of human immunodeficiency virus type 1 (HIV-1), we analyzed the intracellular complexes mediating reverse transcription isolated from acutely infected cells. Partial purification of the reverse transcription complexes (RTCs) by equilibrium density fractionation and velocity sedimentation indicated that two species of RTCs are formed but only one species is able to...

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PMID: 11264352
DOI: 10.1128/jvi.75.8.3626-3635.2001

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