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Article

A genetic screen for attenuated growth identifies genes crucial for intraerythrocytic development of Plasmodium falciparum.

PloS one - 11 Oct 2010

Balu Bharath, Singh Naresh, Maher Steven P, Adams John H

Abstract excerpt

A majority of the Plasmodium falciparum genome codes for genes with unknown functions, which presents a major challenge to understanding the parasite's biology. Large-scale functional analysis of the parasite genome is essential to pave the way for novel therapeutic intervention strategies against the disease and yet difficulties in genetic manipulation of this deadly human malaria parasite have been a major...

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Identifiers

PMID: 20949012
DOI: 10.1371/journal.pone.0013282
PMCID: PMC2952599

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