Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-efficiency transformation of <i>Plasmodium falciparum</i> by the lepidopteran transposable element <i>piggyBac</i>

31 Oct 2005

Abstract excerpt

Functional analysis of the Plasmodium falciparum genome is restricted because of the limited ability to genetically manipulate this important human pathogen. We have developed an efficient transposon-mediated insertional mutagenesis method much needed for high-throughput functional genomics of malaria parasites. A drug-selectable marker, human dihydrofolate reductase, added to the lepidopteran transposon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect Resistance and Genetics
Share to Invertebrate Immune Response Mechanisms
Share to Malaria Research and Control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16260745
DOI: 10.1073/pnas.0504679102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-efficiency transformation of <i>Plasmodium falciparum</i> by the lepidopteran transposable element <i>piggyBac</i>PMID 16260745Read ↗

Functional genomics of Plasmodium falciparum through transposon-mediated mutagenesisSemantic proximity Read ↗

<i>piggyBac</i> transposon remobilization and enhancer detection in <i>Anopheles</i> mosquitoesSemantic proximity Read ↗

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants.Semantic proximity Read ↗

Germline transformation of the West Nile Virus and avian malaria vector <i>Culex quinquefasciatus</i> Say using the piggyBac transposon systemSemantic proximity Read ↗

A genetic screen for attenuated growth identifies genes crucial for intraerythrocytic development of Plasmodium falciparum.Semantic proximity Read ↗

piggyBac-mediated Germline Transformation of the Malaria Mosquito Anopheles stephensi Using the Red Fluorescent Protein dsRED as a Selectable MarkerSemantic proximity Read ↗

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesisSemantic proximity Read ↗

Phenotypic screens reveal Plasmodium falciparum genetic factors associated with infection of sickle-trait cells.Semantic proximity Read ↗

A Conditional Cas9 System for Stage-Specific Gene Editing in <i>P. falciparum</i>Semantic proximity Read ↗

Genetic factors regulating Plasmodium falciparum gametocytogenesis identified by phenotypic screens.Semantic proximity Read ↗

Towards genome-wide experimental genetics in the<i>in vivo</i>malaria model parasite<i>Plasmodium berghei</i>Semantic proximity Read ↗

Manipulating the<i>Plasmodium</i>GenomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.