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Article

miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells.

Oncotarget - 1 Sept 2010

Noonan Emily J, Place Robert F, Basak Shashwati, Pookot Deepa, Li Long-Cheng

Abstract excerpt

MicroRNAs (miRNAs) are a class of small non-coding RNAs (ncRNAs) that regulate gene expression by repressing translation or triggering the degradation of complementary mRNA sequences. Certain miRNAs have been shown to function as integral components of the p53 and/or retinoblastoma (Rb) regulator...

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Source

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Identifiers

PMID: 20948989
DOI: 10.18632/oncotarget.167
PMCID: PMC2952964

Genes

CCND1
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20948989-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells.PMID 20948989Read ↗

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