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Article

MicroRNA‑149 inhibits cancer cell malignant phenotype by regulating Akt1 in C4‑2 CRPC cell line.

Oncology reports - 1 Dec 2021

Zhao Jiahui, Li Qiankun, Feng Bingfu, Wei Dechao, Han Yili, Li Mingchuan, Wang Yongxing, Luo Yong, Jiang Yongguang

Abstract excerpt

Prostate cancer (PCa) is an androgen‑dependent disease. Androgen receptor (AR) has a crucial role in the development and progression of PCa. Recently, several microRNAs (miRNAs/miRs) involved in AR regulation have been associated with castration‑resistant prostate cancer (CRPC), the terminal stage of PCa. Nevertheless, the precise mechanism remains unclear. The present study aimed to identify a novel miR‑149...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34698359
DOI: 10.3892/or.2021.8209
PMCID: PMC8561672

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