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Article

GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer

1 Sept 2019

Abstract excerpt

BACKGROUND: Bladder cancer (BC) is one of the most prevalent malignancies of the genitourinary system, yet the underlying mechanism of BC progression still remains unclear. Growth arrest and DNA damage-inducible 45 alpha (GADD45a) is a repressive gene implicated in cell cycle regulation, as well as in human cancers development. However, its role in BC remains to be determined. METHODS: First, quantitative...

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PMID: 31571910
DOI: 10.2147/ott.s222223

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