Article
Annexin A5 therapy attenuates vascular inflammation and remodeling and improves endothelial function in mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2011
Ewing Mark M, de Vries Margreet R, Nordzell Mariette, Pettersson Knut, de Boer Hetty C, van Zonneveld Anton Jan, Frostegård Johan, Jukema J Wouter, Quax Paul H A
Abstract excerpt
OBJECTIVE: Annexin A5 (AnxA5) has antithrombotic, antiapoptotic, and antiinflammatory properties; we investigated its effectiveness against vascular inflammation, remodeling, and dysfunction in accelerated atherosclerosis. METHODS AND RESULTS: AnxA5 (1 mg/kg per day or vehicle) was investigated i...
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