Article
Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2017
de Jong Renske J, Paulin Nicole, Lemnitzer Patricia, Viola Joana R, Winter Carla, Ferraro Bartolo, Grommes Jochen, Weber Christian, Reutelingsperger Chris, Drechsler Maik, Soehnlein Oliver
Abstract excerpt
OBJECTIVE: Restenosis as a consequence of arterial injury is aggravated by inflammatory pathways. Here, we investigate the role of the proresolving protein annexin A1 (AnxA1) in healing after wire injury. APPROACH AND RESULTS: Apoe-/- and Apoe-/-Anxa1-/- mice were subjected to wire injury while fed a high-cholesterol diet. Subsequently, localization of AnxA1 and AnxA1 plasma levels were examined. AnxA1 was found...
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