Article
Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2011
Nadkarni Suchita, Cooper Dianne, Brancaleone Vincenzo, Bena Stefania, Perretti Mauro
Abstract excerpt
OBJECTIVE: The anti-inflammatory properties of the female sex hormone estrogen have been linked to a reduced incidence of cardiovascular disease. In the present study, we addressed whether estrogen could activate vasculoprotective mechanisms via annexin A1 (AnxA1) mobilization in human polymorpho...
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