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Article

A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma.

Cancer prevention research (Philadelphia, Pa.) - 1 Nov 2010

Merlo Lauren M F, Shah Najaf A, Li Xiaohong, Blount Patricia L, Vaughan Thomas L, Reid Brian J, Maley Carlo C

Abstract excerpt

Neoplastic progression is an evolutionary process driven by the generation of clonal diversity and natural selection on that diversity within a neoplasm. We hypothesized that clonal diversity is associated with risk of progression to cancer. We obtained molecular data from a cohort of 239 partici...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20947487
DOI: 10.1158/1940-6207.CAPR-10-0108
PMCID: PMC3004782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20947487-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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