Article
A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism.
Journal of thrombosis and haemostasis : JTH - 1 Dec 2010
Antoni G, Morange P-E, Luo Y, Saut N, Burgos G, Heath S, Germain M, Biron-Andreani C, Schved J-F, Pernod G, Galan P, Zelenika D, Alessi M-C, Drouet L, Visvikis-Siest S, Wells P S, Lathrop M, Emmerich J, Tregouet D-A, Gagnon F
Abstract excerpt
BACKGROUND: Factor VIII (FVIII) and von Willebrand factor (VWF) are two known quantitative risk factors for venous thromboembolism (VTE). OBJECTIVES: To identify new loci that could contribute to VTE susceptibility and to modulating FVIII and/or VWF levels. PATIENTS/METHODS: A pedigree linkage an...
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