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Article

Genetic variation within the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways as risk factors for venous thromboembolism.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2011

Heit J A, Cunningham J M, Petterson T M, Armasu S M, Rider D N, DE Andrade M

Abstract excerpt

BACKGROUND: Venous thromboembolism (VTE) is highly heritable (estimated heritability [h(2)]=0.62) and likely to be a result of multigenic action. OBJECTIVE: To systematically test variation within genes encoding for important components of the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways for an independent association with VTE. METHODS: Non-Hispanic adults of European ancestry with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21463476
DOI: 10.1111/j.1538-7836.2011.04272.x
PMCID: PMC3110632

Genes

ABO
KLKB1
SCUBE1
SELP
GFRA1

Variants

rs2519093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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