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Article

Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations.

BMC genetics - 13 Oct 2010

Struchalin Maksim V, Dehghan Abbas, Witteman Jacqueline Cm, van Duijn Cornelia, Aulchenko Yurii S

Abstract excerpt

BACKGROUND: Presence of interaction between a genotype and certain factor in determination of a trait's value, it is expected that the trait's variance is increased in the group of subjects having this genotype. Thus, test of heterogeneity of variances can be used as a test to screen for potentially interacting single-nucleotide polymorphisms (SNPs). In this work, we evaluated statistical properties of variance...

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Identifiers

PMID: 20942902
DOI: 10.1186/1471-2156-11-92
PMCID: PMC2973850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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