Article
An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity.
BMC genetics - 24 Jan 2012
Struchalin Maksim V, Amin Najaf, Eilers Paul H C, van Duijn Cornelia M, Aulchenko Yurii S
Abstract excerpt
BACKGROUND: Hundreds of new loci have been discovered by genome-wide association studies of human traits. These studies mostly focused on associations between single locus and a trait. Interactions between genes and between genes and environmental factors are of interest as they can improve our understanding of the genetic background underlying complex traits. Genome-wide testing of complex genetic models is a...
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