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Article

Meta-analysis of SNP-environment interaction with heterogeneity for overlapping data.

Scientific reports - 28 Jan 2021

Jin Qinqin, Shi Gang

Abstract excerpt

Meta-analysis is a popular method used in genome-wide association studies, by which the results of multiple studies are combined to identify associations. This process generates heterogeneity. Recently, we proposed a random effect model meta-regression method (MR) to study the effect of single nucleotide polymorphism (SNP)-environment interactions. This method takes heterogeneity into account and produces high...

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PMID: 33510406
DOI: 10.1038/s41598-021-82336-8
PMCID: PMC7844041

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