Article
Amyotrophic lateral sclerosis.
Lancet (London, England) - 4 Nov 2017
van Es Michael A, Hardiman Orla, Chio Adriano, Al-Chalabi Ammar, Pasterkamp R Jeroen, Veldink Jan H, van den Berg Leonard H
Abstract excerpt
Amyotrophic lateral sclerosis is characterised by the progressive loss of motor neurons in the brain and spinal cord. This neurodegenerative syndrome shares pathobiological features with frontotemporal dementia and, indeed, many patients show features of both diseases. Many different genes and pathophysiological processes contribute to the disease, and it will be necessary to understand this heterogeneity to find...
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