Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections.

doi:10.1371/journal.ppat.1001125

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Article

Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections.

PLoS pathogens - 30 Sept 2010

Levert Maxime, Zamfir Oana, Clermont Olivier, Bouvet Odile, Lespinats Sylvain, Hipeaux Marie Claire, Branger Catherine, Picard Bertrand, Saint-Ruf Claude, Norel Françoise, Balliau Thierry, Zivy Michel, Le Nagard Hervé, Cruveiller Stéphane, Cruvellier Stéphane, Chane-Woon-Ming Béatrice, Nilsson Susanna, Gudelj Ivana, Phan Katherine, Ferenci Thomas, Tenaillon Olivier, Denamur Erick

Abstract excerpt

Although polymicrobial infections, caused by combinations of viruses, bacteria, fungi and parasites, are being recognised with increasing frequency, little is known about the occurrence of within-species diversity in bacterial infections and the molecular and evolutionary bases of this diversity. We used multiple approaches to study the genomic and phenotypic diversity among 226 Escherichia coli isolates from...

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PMID: 20941353
DOI: 10.1371/journal.ppat.1001125
PMCID: PMC2947995

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