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Article

Colistin heteroresistance in Enterobacter due to base heterozygosity at certain phoP and phoQ locations.

Antimicrobial agents and chemotherapy - 5 Nov 2025

Wang Chengcheng, Feng Yu, Zong Zhiyong

Abstract excerpt

Colistin heteroresistance (CHR) is a growing concern in clinical settings. We aimed to investigate CHR for its prevalence in Enterobacter strains, its impact on colistin treatment, and its genetic mechanisms. We analyzed 109 non-duplicated Enterobacter strains isolated from blood cultures. Minimum inhibitory concentrations (MICs) of colistin for each strain were determined using microdilution and CHR was assessed...

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Identifiers

PMID: 40965592
DOI: 10.1128/aac.00713-25
PMCID: PMC12587611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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