Article
Microdiversity of Enterococcus faecalis isolates in cases of infective endocarditis: selection of non-synonymous mutations and large deletions is associated with phenotypic modifications.
Emerging microbes & infections - 1 Dec 2021
Royer G, Roisin L, Demontant V, Lo S, Coutte L, Lim P, Pawlotsky J M, Jacquier H, Lepeule R, Rodriguez C, Woerther P L
Abstract excerpt
Context: Today, infective endocarditis (IE) caused by Enterococcus faecalis represents 10% of all IE and is marked by its difficult management and the frequency of relapses. Although the precise reasons for that remain to be elucidated, the evolution of the culprit strain under selective pressure through microdiversification could be, at least in part, involved. Material and methods: To further study the in situ...
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