Article
A rapid sample method for HLA haplotype typization. A preliminary study on celiac patients.
Minerva stomatologica - 1 Sept 2010
Erriu M, Boscarelli F, Peluffo C, Orrù G, Nucaro A, Zorco S, Santini N, Montaldo C
Abstract excerpt
AIM: The aim of the present work was to determine the human leukocyte (HLA) haplotype in 64 Sardinian patients affected with celiac disease, using a rapid and easy to apply sampling method that permits samples from blood drawing to be stored more easily. Numerous studies have demonstrated how the HLA system plays a very important role in immune system regulation, determining a link between this gene and a high...
Topics
- Adolescent
- Adult
- Aged
- Celiac Disease
- Child
- Child, Preschool
- DNA
- Double-Blind Method
- Epithelial Cells
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Haplotypes
