Article
Allele and haplotype frequencies for HLA-DQ in Iranian celiac disease patients.
World journal of gastroenterology - 28 May 2014
Rostami-Nejad Mohammad, Romanos Jihane, Rostami Kamran, Ganji Azita, Ehsani-Ardakani Mohammad Javad, Bakhshipour Ali-Reza, Zojaji Homayoun, Mohebbi Seyed Reza, Zali Mohammad-Reza, Wijmenga Cisca
Abstract excerpt
AIM: To assess the distribution of human leukocyte antigen (HLA)-DQ2 and -DQ8 in Iranian celiac disease (CD) patients and compare them to healthy Iranian controls. METHODS: To predict the HLA-DQA1 and -DQB1 genes, we used six previously reported HLA-tagging single nucleotide polymorphism to determine HLA genotypes in 59 Iranian patients with 'biopsy-confirmed' CD and in 151 healthy Iranian individuals. To test...
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