Article
Human leukocyte antigen typing using buccal swabs as accurate and non-invasive substitute for venipuncture in children at risk for celiac disease.
Journal of gastroenterology and hepatology - 1 Oct 2016
Adriaanse Marlou P M, Vreugdenhil Anita C E, Vastmans Véronique, Groeneveld Lisette, Molenbroeck Stefan, Schott Dina A, Voorter Christina E M, Tilanus Marcel G J
Abstract excerpt
BACKGROUND AND AIM: Human leukocyte antigen (HLA) typing is an important step in the diagnostic algorithm for celiac disease (CD) and is also used for screening purposes. Collection of blood is invasive and accompanied with emotional impact especially in children. Genetic technological progress now enables HLA typing from buccal cell samples. This study evaluated the reliability and feasibility of HLA typing for...
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