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Article

Transforming growth factor-β and the hallmarks of cancer.

Cellular signalling - 1 Jun 2011

Tian Maozhen, Neil Jason R, Schiemann William P

Abstract excerpt

Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives malignant cells to acquire six phenotypic hallmarks of cancer, including their ability to proliferate and replicate autonomously, to resist cytostatic and apoptotic signals, and to induce tissue invasion, metastasis, and angiogenesis. Transforming growth factor-β (TGF-β) is a potent pleiotropic cytokine that functions as a...

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Identifiers

PMID: 20940046
DOI: 10.1016/j.cellsig.2010.10.015
PMCID: PMC3076078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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