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Article

Broker genes in human disease.

Genome biology and evolution - 1 Jan 2010

Cai James J, Borenstein Elhanan, Petrov Dmitri A

Abstract excerpt

Genes that underlie human disease are important subjects of systems biology research. In the present study, we demonstrate that Mendelian and complex disease genes have distinct and consistent protein-protein interaction (PPI) properties. We show that five different network properties can be redu...

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Identifiers

PMID: 20937604
DOI: 10.1093/gbe/evq064
PMCID: PMC2988523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20937604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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