Article
TNF-α levels are not increased in inflamed patients carrying the CCR5 deletion 32.
Cytokine - 1 Jan 2011
Muntinghe Friso L H, Carrero Juan Jesus, Navis Gerjan, Stenvinkel Peter
Abstract excerpt
BACKGROUND AND AIMS: Recently we reported on a genetically predisposed protection from C-reactive protein (CRP) related mortality in dialysis patients carrying the functional CC-chemokine receptor 5 deletion 32 allele (CCR5Δ32) mutation. Since CCR5Δ32 is associated with a less pro-inflammatory immune response in mice, we hypothesized that the observed protection is (in part) due to a less pro-inflammatory...
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