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Article

Lack of association of C-C chemokine receptor 5 Δ32 deletion status with rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and disease severity.

The Journal of rheumatology - 1 Nov 2010

Martens Henk A, Gross Sacha, van der Steege Gerrit, Brouwer Elisabeth, Berden Jo H M, de Sevaux Ruud, Derksen Ronald H W M, Voskuyl Alexandre E, Berger Stefan P, Navis Gerjan J, Kallenberg Cees G M, Bijl Marc

Abstract excerpt

OBJECTIVE: C-C chemokine receptor 5 (CCR5) plays an important role in inflammation. A 32 base-pair (Δ32) deletion in the CCR5 gene leads to a nonfunctional receptor. This deletion has been reported to have a protective effect on the development and progression of several autoimmune diseases. We investigated whether the Δ32 deletion is associated with disease susceptibility in a population of patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

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Source

Identifiers

PMID: 20682662
DOI: 10.3899/jrheum.091468

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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