Article
Polymorphisms in IFN-γ, TNF-α and IL-10 in patients on maintenance haemodialysis.
Folia biologica - 1 Jan 2011
Bloudíčková S, Kuthanová L, Hubáček J A
Abstract excerpt
The dysbalance in the expression of proinflammatory and anti-inflammatory cytokines, which is partially genetically determined, might have essential impact on the clinical outcome and survival of haemodialysed (HD) patients. A total of 500 HD patients and 500 healthy controls were genotyped for three single-nucleotide polymorphisms (SNPs: TNFA -308G/A, IL10 -1082G/A, IFNG +874A/T). To detect the SNPs' impact on...
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