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Article

Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.

The Journal of clinical investigation - 1 Dec 2006

Masuyama Ritsuko, Stockmans Ingrid, Torrekens Sophie, Van Looveren Riet, Maes Christa, Carmeliet Peter, Bouillon Roger, Carmeliet Geert

Abstract excerpt

Genomic actions induced by 1alpha25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] are crucial for normal bone metabolism, mainly because they regulate active intestinal calcium transport. To evaluate whether the vitamin D receptor (VDR) has a specific role in growth-plate development and endochondral bone formation, we investigated mice with conditional inactivation of VDR in chondrocytes. Growth-plate chondrocyte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17099775
DOI: 10.1172/JCI29463
PMCID: PMC1635166

Genes

VDR
FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

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Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.PMID 17099775Read ↗

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