Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protective effects of FCGR2A polymorphism in invasive pneumococcal diseases.

Chest - 1 Dec 2012

Bouglé Adrien, Max Adeline, Mongardon Nicolas, Grimaldi David, Pène Frédéric, Rousseau Christophe, Chiche Jean-Daniel, Bedos Jean-Pierre, Vicaut Eric, Mira Jean-Paul

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae is a major cause of pneumonia and meningitis. Several genetic polymorphisms have been described to explain differences in susceptibility and severity of encapsulated pathogen-related diseases. Among them, a functional FCGR2A polymorphism leading to amino acid change of histidine (H) to arginine (R) at position 131 appears to be a major candidate in adult invasive pneumococcal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hospital Mortality
Share to Intensive Care Units

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Pneumococcal Infections

Share to Receptors, IgG

Share to Respiration, Artificial

Share to Severity of Illness Index

Share to Survival Rate

Source

Identifiers

PMID: 22628489
DOI: 10.1378/chest.11-2516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protective effects of FCGR2A polymorphism in invasive pneumococcal diseases.PMID 22628489Read ↗

The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.Semantic proximity Read ↗

The Fcgamma receptor IIA-R/R131 genotype is associated with severe sepsis in community-acquired pneumonia.Semantic proximity Read ↗

FcgammaRIIA polymorphisms in Streptococcus pneumoniae infection.Semantic proximity Read ↗

Clinical relevance of TLR2, TLR4, CD14 and FcgammaRIIA gene polymorphisms in Streptococcus pneumoniae infection.Semantic proximity Read ↗

Relationship between Fc receptor IIA polymorphism and infection in children with sickle cell disease.Semantic proximity Read ↗

Association between FcgammaRIIa-R131 allotype and bacteremic pneumococcal pneumonia.Semantic proximity Read ↗

Genetic susceptibility to invasive pneumococcal disease.Semantic proximity Read ↗

Host Genetic Variants Associated with Susceptibility and Severity of Pneumococcal Pneumonia in Adult PatientsSemantic proximity Read ↗

The contribution of genetic variation of <i>Streptococcus pneumoniae</i> to the clinical manifestation of invasive pneumococcal diseaseSemantic proximity Read ↗

Fcgamma-receptor IIA genotype and invasive pneumococcal infection.Semantic proximity Read ↗

The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.Semantic proximity Read ↗

Genetic variants of the MBL2 gene are associated with mortality in pneumococcal sepsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.