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Article

Characterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944.

The Journal of biological chemistry - 10 Dec 2010

Chen Yihua, Wendt-Pienkowski Evelyn, Ju Jianhua, Lin Shuangjun, Rajski Scott R, Shen Ben

Abstract excerpt

Fredericamycin (FDM) A is a pentadecaketide natural product that features an amide linkage. Analysis of the fdm cluster from Streptomyces griseus ATCC 43944, however, failed to reveal genes encoding the types of amide synthetases commonly seen in natural product biosynthesis. Here, we report in v...

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Identifiers

PMID: 20926388
DOI: 10.1074/jbc.M110.147744
PMCID: PMC2998092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20926388-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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