Article
Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.
Cancer - 15 Feb 2011
Tanaka Motofumi, Okazaki Taro, Suzuki Hideo, Abbruzzese James L, Li Donghui
Abstract excerpt
BACKGROUND: The purpose of this study was to identify single nucleotide polymorphisms (SNPs) of multidrug resistance genes that are associated with clinical outcome in patients with potentially resectable pancreatic adenocarcinoma who were treated with preoperative gemcitabine-based chemoradiotherapy at M. D. Anderson Cancer Center. METHODS: We selected 8 SNPs of 7 drug resistance genes, including MDR1 (ABCB1),...
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