Article
Neuropeptide Y: identification of the binding site.
International journal of peptide and protein research - 1 Dec 1990
Beck-Sickinger A G, Gaida W, Schnorrenberg G, Lang R, Jung G
Abstract excerpt
Based on the hypothetical 3D structure of neuropeptide Y (NPY), NPY 1-4-Aca-25-36, a 17 amino acid analogue, has been synthesized replacing the sequence NPY 5-24 by epsilon-aminocaproic acid (Aca). This low-molecular weight deletion analogue showed nearly comparable receptor affinity to NPY. In o...
Topics
- Alanine
- Amino Acid Sequence
- Binding Sites
- Genetic Variation
- Glycine
- Molecular Sequence Data
- Neuropeptide Y
- Protein Conformation
- Stereoisomerism